The Journal of Phytopharmacology, 2020;9(5):356-360 ; DOI:10.31254/phyto.2020.9511
In vitro anti-inflammatory activity of aqueous extract of Albizia lebbeck leaf (l.)
Kamala Lakshmi B1 , Valarmathi S2
1. Department of Biochemistry PSG College of Arts & Science Coimbatore, Tamil Nadu, India
2. Assistant Professor, Department of Biochemistry PSG College of Arts & Science
*Author to whom correspondence should be addressed.
Received: 20th August, 2020 / Accepted: 25th September, 2020
Albizia lebbeck (L.) Benth is an important traditional tree found throughout India. All part of this tree is considered as folk medicine and used for treatment of various disease. Current research work was carried out to identify the bioactive compound by phytochemical screening and to evaluate anti-inflammatory potential of aqueous leaf extract of A. lebbeck. The phytochemical screening of the leaf of A. lebbeck shows the presence of alkaloid, flavonoid, tannin, phenol, saponin, glycoside and free amino acid. The maximum inhibition of protein denaturation was found to be 78.06±0.5% at 500 µg/mL concentration and its IC?? was 330 µg/mL concentration. The maximum inhibition in membrane stabilization was found to be 74.09±0.33% at 500 µg/mL concentration and its IC?? was 440 µg/mL concentration. The maximum protection in hypotonicity induced haemolysis shows about 69.34±0.38% at 500 µg/mL concentration and its IC?? was 400 µg/mL concentration. In vitro assay shows the moderate activity of anti-inflammatory in aqueous extract of A. lebbeck, when compared with the standard.
Albizia lebbeck, Anti-inflammatory, Denaturation, Membrane stabilization.
HOW TO CITE THIS ARTICLE
Kamala Lakshmi B, Valarmathi S. In vitro anti-inflammatory activity of aqueous extract of Albizia lebbeck leaf (l.). J Phytopharmacol 2020; 9(5):356-360.
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