ISSN: 2320-480X
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The Journal of Phytopharmacology, 2017;6(5):297-299 ;   DOI:10.31254/phyto.2017.6508

Research Article

In vitro Anti-coagulant Activity of Dalbergia sissoo Bark

Jyoti B Wadekar1 , Ramesh L Sawant2 , Sachin V Kirtane1 , Kunal R Sanklecha2 , Amol S Ghodechor2 , Bhagyashri B More1 , Varsha R Raut1

1. Department of Pharmacognosy, Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahmednagar, Maharashtra-414111, India
2. Department of Pharmaceutical Chemistry, Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahmednagar, Maharashtra414111, India

*Author to whom correspondence should be addressed.

Received: 23rd September, 2017 / Accepted: 11th November, 2017

Abstract


Dalbergia sissoo belonging to family Fabaceae is a widely growing plant and has been reported to possess multiple therapeutic properties like analgesic, anti-inflammatory, analgesic and antipyretic anti-ulcer, antioxidant, anthelmintic, antimicrobial, antidiabetic and is also used to treat syphilis, dysentery, nausea, eye and nose disorder, skin diseases and blood disorder. However, the plant yet has not been fully elucidated for its anti-coagulant property. Hence, in the present investigation an attempt has been made to explore the anticoagulant potential of Dalbergia sissoo bark in comparison with a known standard drug as the positive control and normal saline as the negative control. The anti-coagulant activity of the aqueous and alcoholic extract of Dalbergia sissoo bark may be due to presence of phytochemicals such as flavonoids and phenolic compounds which reveals on preliminary phytochemical screening.

Keywords

Dalbergia sissoo, Quick‘s method, Prothrombin time, Phenolic compounds, Flavonoid.


HOW TO CITE THIS ARTICLE

Wadekar JB, Sawant RL, Kirtane SV, Sanklecha KR, Ghodechor AS, More BB, Raut VR. In vitro Anti-coagulant Activity of Dalbergia sissoo Bark. J Phytopharmacol 2017; 6(5):297-299.

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Copyright © 2017 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0.

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