The Journal of Phytopharmacology, 2015;4(4):202-206 ; DOI:10.31254/phyto.2015.4402
Butanol soluble fractions of Cissus cornifolia methanolic leaf extract and behavioural effects in mice
Abdullahi Hamza Yaro1 , Musa Aliyu Muhammad2 , Abdullahi Balarabe Nazifi1 , Mohammed Garba Magaji3
1. Department of Pharmacology, Bayero University, Kano, Nigeria
2. Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria
3. Department of Pharmacology and Therapeutics, Ahmadu Bello University, Zaria, Nigeria
*Author to whom correspondence should be addressed.
Cissus cornifolia Baker - Planch (Family: Vitaceae) is used for various central nervous system disorders. The present study reported the sedative and central nervous depressant effects of fractions (butanol soluble portion and its flavonoid rich fraction) obtained from methanolic leaf extract of Cissus cornifolia using diazepam induced sleep, head-dip and motor coordination tests in mice at doses between 5 to 600 mg/kg body weight. The flavonoid rich column fraction 3 (CF3) significantly (p
Behaviour, Cissus cornifolia, Diazepam, Flavonoid.
HOW TO CITE THIS ARTICLE
Yaro AH, Muhammad M.A, Nazifi AB, Magaji MG. Butanol soluble fractions of Cissus cornifolia methanolic leaf extract and behavioural effects in mice . The Journal of Phytopharmacology 2015; 4 ( 4):202 -206 .
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