ISSN: 2320-480X
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The Journal of Phytopharmacology, 2021;10(6):496-499 DOI:10.31254/phyto.2021.10611

Research Article

Evaluation of acute oral toxicity of a herbal semen quality enhancer

Sunil Hajare1 , Ranjit Suresh Ingole1 , Mahesh Kumar Vitthal Ingawale1 , Vivek Borekar1 , David Kumar2 , Ravikanth Kotagiri2 , Bhaskar Ganguly2

1. Post Graduate Institute of Veterinary and Animal Sciences (PGIVAS), Akola - 444104, India
2. Research and Development Unit, Ayurvet Limited, Baddi - 173205, India

*Author to whom correspondence should be addressed.

Received: 30th October, 2021 / Accepted: 16th December, 2021

Abstract


The objective of this study was to assess the acute oral toxicity of AV/SGB/27 (M/s Ayurvet Limited) in accordance with OECD-423 guideline. AV/SGB/27 is a herbal formulation for enhancing semen quality of livestock. Nine healthy and adult nulliparous nonpregnant Swiss albino female mice, weighing 24-28 g, were used in this study. After being given test material orally, the mice were examined for toxic effects and mortality. Changes in body weights, symptoms of toxicity, histological appearances of liver, kidney, and lungs, and biochemical parameters were used to assess the toxicity. No toxic effects or mortalities were noticed until the trial was completed, indicating that AV/SGB/27 is safe for oral consumption.

Keywords


Acute oral toxicity, AV/SGB/27, OECD 423, Semen quality, Herbal

HOW TO CITE THIS ARTICLE

Hajare S, Ingole RS, Ingawale MKV, Borekar V, Kumar D, Kotagiri R, et al. Evaluation of acute oral toxicity of a herbal semen quality enhancer. J Phytopharmacol 2021; 10(6):496-499. doi: 10.31254/phyto.2021.10611

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This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY 4.0) license. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (http://creativecommons.org/licenses/by/4.0/).

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Copyright © 2021 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0.

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