The Journal of Phytopharmacology, 2020;9(5):333-341 DOI:10.31254/phyto.2020.9508
Reproductive potency of methanolic bi-herbal (Zingiber officinale and Chrysophyllum albidum) extract on masculine wistar rats
Gabriel Ogunma Benjamin1 , Emmanuel Ola Oshomoh2 , Asuelimen Osagie Steve3 , Otakhor Kelly Osayi4
1. Phytomedicine Unit, University of Benin, PMB 1154, Benin City, Edo State. Nigeria
2. Department of Science Laboratory Technology, Faculty of Life Sciences, University of Benin, Edo State. Nigeria
3. Department of Biochemistry, Federal University Wukari, Taraba State. Nigeria
4. Department of Physiology, College of Medicine, Uniben, Benin City, Edo State. Nigeria
*Author to whom correspondence should be addressed.
Received: 28th July, 2020 / Accepted: 23rd August, 2020
The study is aimed at evaluating the fertility potential of bi-herbal methanol extract on male Wistar rats. This research finding based it fact of fertility in male Wistar rats to investigate through the phytochemicals, antioxidant assay, hormonal indexes, lipid profile, body/organ weight changes and histopathological study across the graded doses (25, 50, 100 mg/kg) of the treated groups of bi-herbal (Zingiber officinale and Chrysophyllum albidum)) methanol extract using standard procedure. Results from the phytochemical screening elicited the essential constituents (alkaloids, flavonoids phenol, tannins and saponnins). The antioxidant assay showed broad scavenging property against free radicals, which possibly is associated with one of its mechanisms of action. An increase in the level of significant (p > 0.05) in hormonal indexes (testosterone, progesterone, follicle stimulating hormone and luteinizing hormone) and slight increase in the level of lipid profile (cholesterol, triglyceride, HDL LDL and VLDL) activities among the treatment groups when compared with the control. There absent significant change (p > 0.05) in the body and testes mass ratio. No pronounce histopathological variation on the testes state in comparative to the control. The dependent from the bi-herbal extract with extreme exhibition of fertility potential as its therapeutic effect.
Reproductive fertility, Bi-herbal, Zingiber officinale, Chrysophyllum albidum. Masculine Wistar rats.
HOW TO CITE THIS ARTICLE
Benjamin GO, Oshomoh EO, Steve AO, Osayi OK. Reproductive potency of methanolic bi-herbal (Zingiber officinale and Chrysophyllum albidum) extract on masculine wistar rats. J Phytopharmacol 2020; 9(5):333-341.
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