ISSN: 2320-480X
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The Journal of Phytopharmacology, 2019;8(2):75-83 ;   DOI:10.31254/phyto.2019.8210

Review Article

Significance of Antioxidants in the Treatment and Prevention of Neurodegenerative Diseases

Adewale Oluwaseun Fadaka1,2 , Basiru Olaitan Ajiboye2 , Ifanikin Adewale2 , Oluwafemi Adeleke Ojo3 , Babatunji Emmanuel Oyinloye2 , Mary Abiola Okesola4

1. Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Cape Town, South Africa.
2. Department of Biochemistry Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria
3. Department of Biochemistry, University of Ilorin, Ilorin, Nigeria
4. Department of Biochemistry, Covenant University, Ota, Nigeria

*Author to whom correspondence should be addressed.

Received: 17th February, 2019 / Published : 20th April, 2019

Abstract


Neurodegenerative diseases are ailments that disturb the brain, precisely the neurons. The utmost mutual indicators include failures in stability, inhalation, movement, reflexes, motor skills or heartbeat activity. These can be prevented using ordinary antioxidants, like vitamins E and C, flavonoids, and polyphenols compounds. Antioxidants show a substantial effect in human’s health since they can ameliorate aging by fighting free radicals. Precisely Vitamin C can serve as a commanding antioxidant in reducing the consequence of oxidative injury triggered by pollutants, anxiety and poor diets amongst others. Thereby reducing the long-term risk of neurodegenerative diseases. Currently, neurodegenerative diseases have no cure, but they can be managed. This diseases management reduces the symptoms so as to sustain the value of life. Management with natural antioxidants such as polyphenols through diet or dietary supplements with lots of benefits have become an attractive alternative. The present knowledge on antioxidant in the treatment of neurodegenerative disorders and future bearings will be discussed and also assess the value for antioxidants as neuroprotective.

Keywords

Neurodegenerative diseases; vitamins; antioxidants; Neuroprotectives; Alzheimer’s disease; Parkinson’s disease.


HOW TO CITE THIS ARTICLE

Fadaka AO, Ajiboye BO, Adewale I, Ojo OA, Oyinloye BE, Okesola MA. Significance of Antioxidants in the Treatment and Prevention of Neurodegenerative Diseases. J Phytopharmacol 2019; 8(2):75-83.

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This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY 4.0) license. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (http://creativecommons.org/licenses/by/4.0/).

Copyright

Copyright © 2019 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0.

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