The Journal of Phytopharmacology, 2019;8(6):291-294 ; DOI:10.31254/phyto.2019.8604
Isolation and NMR Characterisation of a Pentacyclic Triterpenoid from chloroform fraction of Ageratum conyzoides Linn stem bark
Ahamefula A Ahuchaogu1 , Johnbull O Echeme2
1. Department of Pure and Industry Chemistry, Abia state University, Uturu. Nigeria
2. Department of Chemistry, Michael Okpara university of Agriculture, Umudike
*Author to whom correspondence should be addressed.
Received: 15th September, 2019 / Accepted: 11th November, 2019
This study was carried out to identify the bioactive constituents of the stem barks of Ageratum conyzoides Linn a medicinally important plant of the Asteraceae family. This plant was selected on the basis of its widespread use in traditional herbal medicine A pentacyclic triterpenoid lupeol was isolated from the chloroform soluble fraction of the ethanol extract of the stem barks of Ageratum conyzoides a plant know to have potent pharmacological properties, antiangiogenic, antioxidative and anti-inflammatory in nature using a combination of silica gel column chromatography and preparative TLC. The structure of this compound was elucidated using NMR spectroscopic analysis (1D& 2D) FTIR and MS, by comparison with reported data. This is the first report of isolation of this compound from Ageratum conyzoides.
Medicinal plant, Ageratum conyzoides, chloroform fraction, NMR, anti-inflammatory.
HOW TO CITE THIS ARTICLE
Ahamefula AA, Johnbull OE. Isolation and NMR Characterisation of a Pentacyclic Triterpenoid from chloroform fraction of Ageratum conyzoides Linn stem bark. J Phytopharmacol 2019; 8(6):291-294.
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