The Journal of Phytopharmacology, 2018;7(1):60-65 ; DOI:10.31254/phyto.2018.7113
Investigation of anti-arthritic activity (in-vitro models) of Hibiscus hispidissimus Griffith
Shilpa K1 , Nimmy Chacko1 , Prerana Shetty2 , Sandhya Savithri A1
1. Department of Pharmacology, NGSMIPS Mangalore, Karnataka-575018, India
2. Department of Chemistry, NGSMIPS Mangalore, Karnataka-575018, India
*Author to whom correspondence should be addressed.
Received: 17th September, 2017 / Accepted: 2nd November, 2018
Aim of the experiment: The present study was designed to investigate the anti-arthritic potential of the plant Hibiscus hispidissimus. Materials and Methods: The aerial parts of the plant was collected, dried and extracted (maceration) with ethanol. Preliminary phytochemical studies were carried out. All the in-vitro models i.e. inhibition of protein denaturation, membrane stabilization and proteinase inhibition were carried out with standard reference drug diclofenac sodium. Result: Dose dependent and significant (p
Anti-arthritic activity, Hibiscus hispidissimus, inhibition of protein denaturation, membrane stabilization, proteinase inhibition, in-vitro studies.
HOW TO CITE THIS ARTICLE
Shilpa K, Chacko N, Shetty P. Investigation of anti-arthritic activity (invitro models) of Hibiscus hispidissimus Griffith. J Phytopharmacol 2018; 7(1):60-65.
Creative Commons (CC) License-
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY 4.0) license. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (http://creativecommons.org/licenses/by/4.0/).
Copyright
Copyright © 2018 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0.