The Journal of Phytopharmacology, 2018;7(3):285-287 ; DOI:10.31254/phyto.2018.7309
In-vitro evaluation of Scoparia dulcis Linn. for anti – urolithiatic activity
Hima Sasidharan1 , Suma Venkatesh Mallya2 , Prabhu Suchitra3 , Koppala Narayana Sunil Kumar4
1. PG Scholar, Shree Dharmasthala Manjunatheshwara College of Ayurveda, Kuthpady, Udupi, 574118, Karnataka, India
2. Associate Professor, Shree Dharmasthala Manjunatheshwara College of Ayurveda, Kuthpady, Udupi, 574118, Karnataka, India
3. Research Officer, Shree Dharmasthala Manjunatheshwara College of Ayurveda, Kuthpady, Udupi, 574118, Karnataka, India
4. Research Officer, Department of Pharmacognosy, Siddha Central Research Institute, Central Council for Research in Siddha, Ministry of AYUSH, Govt. of India, Arumbakkam, Chennai 600106, Tamil Nadu, India
*Author to whom correspondence should be addressed.
Received: 27th February, 2018 / Accepted: 26th April, 2018
Introduction: Urolithiasis is a complex process that occurs from series of several physicochemical event including super-saturation, nucleation, growth, aggregation and retention within the kidneys. Data from invitro, in- vivo and clinical trials reveal that phytotherapeutic agents could be useful as either alternative or an adjunct therapy in the management of Urolithiasis. Scoparia dulcis (L.) have been reported to possess antiurolithiatic property by various folk lore practitioners. Methods: The in- vitro antiurolithiatic study of the whole plant of S. dulcis (L). through titrimetric and turbidity method to check their potential in dissolving calcium oxalate crystals using Cystone as the standard compound Result: The aqueous extract showed relatively higher dissolution of 66.96% of stones than the alcoholic extract. The turbidity showed by the alcohol extract and the aqueous extract of test drug (S. dulcis (L).) was highly significant compared to the standard (Cystone).
Urolithiasis, in vitro, Scoparia dulcis (L.) titrimetric, turbidity.
HOW TO CITE THIS ARTICLE
Sasidharan H, Mallya SV, Suchitra P, Kumar KNS. In-vitro evaluation of Scoparia dulcis Linn. for anti–urolithiatic activity. J Phytopharmacol 2018; 7(3):285-287.
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