The Journal of Phytopharmacology, 2022;11(6):425-431 ;   DOI:10.31254/phyto.2022.11609

Review Article

Lupeol: An Alternative Approach towards Cancer Treatment

Devender Sharma¹ , Niraj Gupta²

Devender Sharma,Niraj Gupta

1. Research Scholar, School of Pharmacy, OPJS University, Churu, Rajasthan, India
2. Associate Professor, College of Pharmacy Agra, Dr. A.P.J. Abdul Kalam Technical University, Lucknow, Uttar Pradesh

*Author to whom correspondence should be addressed.

Received: 3rd October, 2022 / Accepted: 19th November, 2022 / Published : 20th December, 2022

Abstract

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Cancer is a broad word for a group of neoplastic illnesses defined by changes in a cell's structure that cause it to proliferate abnormally. There are about 200 cancers detected in human body. Each type of carcinoma has different indications and symptoms, as well as different treatments. Lupeol 280 mg/g dried leafs is a chemical component found in aloe leaves. Lupeol is a triterpene active in both food and medicine. Over the last decade, an unprecedented massive increase in involvement in triterpene as a result of their cholesterol-lowering properties. The products based on triterpene are commercially over sold in the world due to its heavy demand of use. Fagarsterol another name for the chemical lupeol. It's found in foods like Brassica oleracea var. capitata, Capsicum annuum Group, Fragaria, Olea europaea, Mangifera indica, Vitis vinifera, Aloe barbandesismiller, Semaltreeetc. Lupeol was already demonstrated to be an efficient curative and protective constituent for a wide range of disorders. It is an anti-carcinogenic and curative compound. Many developments have been so far with respective lupeol dosage formulation to increase bioavailability and pharmacological effect. This manuscript also provides deep inside of recent patents associated with lupeol in past decade.

Keywords

Cancer, Leukemia, Lymphoma, Myeloma, Lupeol, Aloe vera

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