The Journal of Phytopharmacology, 2019;8(6):291-294 DOI:10.31254/phyto.2019.8604
Isolation and NMR Characterisation of a Pentacyclic Triterpenoid from chloroform fraction of Ageratum conyzoides Linn stem bark
Ahamefula A Ahuchaogu1 , Johnbull O Echeme2
1. Department of Pure and Industry Chemistry, Abia state University, Uturu. Nigeria
2. Department of Chemistry, Michael Okpara university of Agriculture, Umudike
*Author to whom correspondence should be addressed.
Received: 15th September, 2019 / Accepted: 11th November, 2019
This study was carried out to identify the bioactive constituents of the stem barks of Ageratum conyzoides Linn a medicinally important plant of the Asteraceae family. This plant was selected on the basis of its widespread use in traditional herbal medicine A pentacyclic triterpenoid lupeol was isolated from the chloroform soluble fraction of the ethanol extract of the stem barks of Ageratum conyzoides a plant know to have potent pharmacological properties, antiangiogenic, antioxidative and anti-inflammatory in nature using a combination of silica gel column chromatography and preparative TLC. The structure of this compound was elucidated using NMR spectroscopic analysis (1D& 2D) FTIR and MS, by comparison with reported data. This is the first report of isolation of this compound from Ageratum conyzoides.
Medicinal plant, Ageratum conyzoides, chloroform fraction, NMR, anti-inflammatory.
HOW TO CITE THIS ARTICLE
Ahamefula AA, Johnbull OE. Isolation and NMR Characterisation of a Pentacyclic Triterpenoid from chloroform fraction of Ageratum conyzoides Linn stem bark. J Phytopharmacol 2019; 8(6):291-294.
Creative Commons (CC) License-
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY 4.0) license. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (http://creativecommons.org/licenses/by/4.0/).
Copyright
Copyright © 2019 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0.