The Journal of Phytopharmacology, 2017;6(5):297-299 DOI:10.31254/phyto.2017.6508

Research Article

In vitro Anti-coagulant Activity of Dalbergia sissoo Bark

Jyoti B Wadekar¹ , Ramesh L Sawant² , Sachin V Kirtane¹ , Kunal R Sanklecha² , Amol S Ghodechor² , Bhagyashri B More¹ , Varsha R Raut¹

Jyoti B Wadekar,Ramesh L Sawant,Sachin V Kirtane,Kunal R Sanklecha,Amol S Ghodechor,Bhagyashri B More,Varsha R Raut

1. Department of Pharmacognosy, Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahmednagar, Maharashtra-414111, India
2. Department of Pharmaceutical Chemistry, Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahmednagar, Maharashtra414111, India

*Author to whom correspondence should be addressed.

Received: 23rd September, 2017 / Accepted: 11th November, 2017

Abstract

Dalbergia sissoo belonging to family Fabaceae is a widely growing plant and has been reported to possess multiple therapeutic properties like analgesic, anti-inflammatory, analgesic and antipyretic anti-ulcer, antioxidant, anthelmintic, antimicrobial, antidiabetic and is also used to treat syphilis, dysentery, nausea, eye and nose disorder, skin diseases and blood disorder. However, the plant yet has not been fully elucidated for its anti-coagulant property. Hence, in the present investigation an attempt has been made to explore the anticoagulant potential of Dalbergia sissoo bark in comparison with a known standard drug as the positive control and normal saline as the negative control. The anti-coagulant activity of the aqueous and alcoholic extract of Dalbergia sissoo bark may be due to presence of phytochemicals such as flavonoids and phenolic compounds which reveals on preliminary phytochemical screening.