The Journal of Phytopharmacology, 2014;3(4):238-241 DOI:10.31254/phyto.2014.3403
Effect of aqueous extract of Talinum triangulae (water leave) in lead- induced chromosomal aberration
Afolabi Olakunle B.1 , Oloyede O.I2 , Oladimeji Tugbobo3
1. Department of Chemical Science, College of Science, Afe Babalola University, P.M.B 5454, Ado- Ekiti, Ekiti State, Nigeria
2. Department of Biochemistry, Faculty of Science, Ekiti State University, Ado-Ekiti, Ekiti State, Nigeria
3. Biochemistry Unit,Department of Science Technology, Federal Polytechnic, Ado- Ekiti, Ekiti State, Nigeria
*Author to whom correspondence should be addressed.
Phytomedicine is a subject that is now gaining relevance worldwide aiding treatment for diseases that were once incurable among folks in which genotoxicity is a prominent one. The present study was designed to examine the ability of Talinum triangulare (water leaf) to protect the genomic integrity of swiss albino rat from lead-induced chromosomal damage in the bone marrow red blood cells. 20 eight week old rats were divided into five groups with group 1 as the negative control and group 2 is the positive control and the other groups, all treated by gavage once per day with a single dose of 2.5 mg/ml lead acetate. The frequency of micronuclei formed was examined in the bone marrow erythroblast of the treated and untreated groups through standard micronuclei assay method. The plant shows significant (p
Talinum triangulare, Genotoxicity, Micronuclei, Polychromatophilc, Erythroblast.
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