The Journal of Phytopharmacology, 2016;5(6):242-247 DOI:10.31254/phyto.2016.5607
An impact of Mardana- A comperative study on Arogyavardhini Rasa
Yuga Raj Sapkota1 , Prashant Bedarakar2 , Galib3 , V.J. Shukla4 , P.K. Prajapati5
1. PhD Scholar, Department of Rasashastra & Bhaishajya Kalpana, Institute for Post Graduate Teaching & Research in Ayurveda (IPGT & RA), Gujarat Ayurved University (GAU), Jamnagar361008, Gujarat, India
2. Assistant Professor, Department of Rasashastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching & Research in Ayurveda (IPGT & RA), Gujarat Ayurved University (GAU), Jamnagar-361008, Gujarat, India
3. Associate Professor, Department of Rasashastra and Bhaishajya Kalpana, All India Institute of Ayurveda (AIIA), New Delhi-110076, Delhi, India
4. Head, Pharmaceutical Chemistry lab, Institute for Post Graduate Teaching & Research in Ayurveda (IPGT & RA), Gujarat Ayurved University (GAU), Jamnagar-361008, Gujarat, India
5. Professor and Dean, All India Institute of Ayurveda (AIIA), New Delhi110076, Delhi, India
*Author to whom correspondence should be addressed.
Background: Arogyavardhini Rasa (AVR); a Kharaliya Rasakalpa containing rasavarga dravya (metallomineral ingredients) is widely used Ayurvedic herbo-mineral formulation having broad spectrum therapeutic indications. Current research is first effort to scientifically document quality control parameters of this important formulation. Aim: To establish a comparative pharmaceutico - analytical profile of AVR prepared with and without its metallomineral ingredients. Materials & Methods: Arogyavardhini Rasa (AVR) and modified Arogyavardhini Rasa (MAVR) without addition of its metallomineral ingredients were prepared and investigated for Physico-chemical parameters, qualitative tests for functional groups, Chromatography, quantitative elemental analysis by ICP-AES. Results & Discussion: An average of 2500ml Swarasa was required for optimum Mardana in both formulations. HPTLC study revealed a total of 11 and 8 bands at 254nm and 366nm in each AVR and MAVR with only two similar Rf values. Samples AVR, MAVR and MAVR with addition of Rasa Dhatukajjali showed 1.5226, 0.0117 and 1.703 % of mercury respectively. Conclusion: Mardana play significant role in development of Kharaliya Rasakalpa Both the formulations showed different through physicochemical profiles and ICP-AES analysis. Differences in chromatographic fingerprinting of AVR and MAVR are suggestive of changes in chemical constituents of the formulation due to addition of metallo minerals.
Arogyavardhini Rasa, Bhasma, HPTLC, Heavy metal, Organometallic, Rasaushadhi, Mercurials.
HOW TO CITE THIS ARTICLE
Sapkota YR, Bedarkar P, Galib, Shukla VJ, Prajapati PK. An impact of Mardana- A comperative study on Arogyavardhini Rasa. J Phytopharmacol 2016;5(6):242-247.
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