The Journal of Phytopharmacology 2023; 12(5):295-298 DOI:10.31254/phyto.2023.12503

Research Article

Antimicrobial activity of Artemisia annua L and Aloe barbadense miller plant extracts against Staphylococcus aureus

Lusweti Kituyi¹ , Samson M. Lutta¹ , Steve Barasa¹

Lusweti Kituyi,Samson M. Lutta,Steve Barasa

1. Department of Chemistry and Biochemistry, University of Eldoret, P.O Box 1125-31000 Eldoret, Kenya

*Author to whom correspondence should be addressed.

Received: 14th May, 2023 / Accepted: 19th October, 2023

Abstract

Artemisia annua L. and Aloe barbadense miller are medicinal plants applied in treatment of various diseases. Staphylococcus aureus is a gram-negative bacterium found commonly on the skin and in the environment. Phytochemical are plants secondary metabolites with promising medicinal properties as remedy to limitations associated with the conventional drugs. A study was conducted to investigate the anti-microbial properties of bioactive components from natural leave extracts of Artemisia annua L. and Aloe barbadensis miller obtained from methanolic as extractant against Staphylococcus aureus. The phytochemical analysis revealed the leave extracts contained most plant secondary metabolites. The biochemical components from both plants were established to inhibit the growth of Staphylococcus aureus. Artemisia annua L had an inhibition zone of 20.67 mm while Aloe barbadensis miller had 10.33 mm against Staphylococcus aureus. The anti-microbial activity of the combined leaves extracts displayed significant high levels of synergetic properties with an inhibition zone of 23.67 mm. Gentamicin which served as standard for the assay had an inhibition zone of 27.67 mm. The study hence showed Artemisia annua L and Aloe barbadensis miller leaves bioactive components can be applied as an effective alternative medicine in management of Staphylococcus aureus.