The Journal of Phytopharmacology 2023; 12(5):305-310 DOI:10.31254/phyto.2023.12505
Phytochemical screening and antimicrobial activity of the plant extracts Andrographis paniculata against selected microbes
Salma Fathima1 , Pruthvi Charan Jambiga1 , Ramya Thumma1 , Samreen Ahmadi1 , Srinitha Askani1 , Bushra Sumayya Mohammed1 , Poornesh Sutramay1 , Sunitha Bai Dharavath2 , Shasthree Taduri2
1. Master student, Department of Biotechnology, Kakatiya University, Warangal 506009, Telangana State, India
2. Department of Biotechnology, Kakatiya University, Warangal 506009, Telangana State, India
*Author to whom correspondence should be addressed.
Received: 24th August, 2023 / Accepted: 31st October, 2023
Background: Andrographis paniculata is a medicinal plant with a long history of traditional use in various herbal medicine systems. Objective: This study aims to conduct aphytochemical screening and antibacterial activity from leaf, stem and root parts of Andrographis paniculata. Methods: The preliminary screening was done by cold maceration technique using chloroform, butanol, methanol, ethanol and aqueous solvents. This phytochemical screening showed the presence of alkaloids, glycosides, flavonoids, terpenoids, phenols, tannins and saponins. Antibacterial activity was performed by using well diffusion method from leaf, stem and root butanolic extracts of A. paniculata. Results: Glycosides are abundantly present in leaf, stem and root explant extracts. Whereas, alkaloids and flavonoids are moderately present in leaf, stem and root explant extracts and followed by less presence of tannins, phenols and saponins. The maximum zone of bacterial inhibition was observed in leaf butanolic extracts against of the E. coli, for stem butanolic extract against of B. subtilis and for root butanolic extract against B. sphaericus. Conclusion: This study revealed the potential photochemical constituents and antibacterial activity in A. paniculata. The presence of these bioactive substances they use in treatment.
Phytochemicals, Glycosides, Alkaloids, Flavonoids, Terpenoids, Phenols
HOW TO CITE THIS ARTICLE
Fathima S, Jambiga PC, Thumm Ra, Ahmadi S, Askani S, Mohammed BS, Sutramay P, Dharavath SB, Taduri S. Phytochemical screening and antimicrobial activity of the plant extracts Andrographis paniculata against selected microbes. J Phytopharmacol 2023; 12(5):305-310. doi: 10.31254/phyto.2023.12505
Creative Commons (CC) License-
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY 4.0) license. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (http://creativecommons.org/licenses/by/4.0/).
Copyright
Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0.