The Journal of Phytopharmacology 2024; 13(2):133-142 DOI:10.31254/phyto.2024.13207
Exploring Bioactive Compounds in Cajanus cajan (L.) Millsp. Stem and their biological activities: Integration of GC-MS and LC-MS Techniques
Jaysing Mahavirsing Dinore1 , Harshal Shivaji Patil2 , Samreen Fatema Farooqui3 , Krishna Raju Nagare4 , Jalindar Sakharam Ambhore5 , Mazahar Farooqui6
1. Assistant Professor, Department of Chemistry, Indraraj Arts, Commerce and Science College, Sillod, Aurangabad, Maharashtra- 431112, India
2. Assistant Professor, Department of Chemistry, Moreshwar Arts, Commerce and Science College, Bhokardan, Jalna, Maharashtra- 431114, India
3. Assistant Professor, Post Graduate and Research Center, Maulana Azad College, Aurangabad, Maharashtra- 431001, India
4. Assistant Professor, Department of Zoology, Indraraj Arts, Commerce and Science College, Sillod, Aurangabad, Maharashtra- 431112, India
5. Professor, Department of Botany, Indraraj Arts, Commerce and Science College, Sillod, Aurangabad, Maharashtra- 431112, India
6. Principal, Maulana Azad College of Arts, Science and Commerce, Aurangabad, Maharashtra- 431001, India
*Author to whom correspondence should be addressed.
Received: 11th February, 2024 / Accepted: 26th April, 2024 / Published : 30th April, 2024
Cajanus cajan, a well-known legume crop with nutritional significance, has been used traditionally for various therapeutic purposes. Despite its ethnomedicinal importance and rich metabolite composition, there have been limited investigations into the secondary metabolites present in its stems using advanced analytical techniques. This study aimed to enhance our understanding of the chemical composition and biological activities of underutilized C. cajan stems. GC-MS & LC-MS analysis revealed flavonoids as the stem's predominant secondary metabolites. The methanol extract exhibited potent antibacterial activity against E. coli, S. aureus, and C. albicans. Major bioactive compounds, including rutin, apiin, quercetrin, and aesculine, contributed to these beneficial effects. The study also revealed a high total phenolic content of 121.5 mg GAE/g in the stem extract, further establishing C. cajan stems as a valuable source of therapeutic molecules.
Cajanus cajan, GC-MS, LC-MS, Antioxidant, Antimicrobial, Total phenolic content
HOW TO CITE THIS ARTICLE
Dinore JM, Patil HS, Farooqui SF, Nagare KR, Ambhore JS, Farooqui M. Exploring Bioactive Compounds in Cajanus cajan (L.) Millsp. Stem and their biological activities: Integration of GC-MS and LC-MS Techniques. J Phytopharmacol 2024; 13(2):133-142. doi: 10.31254/phyto.2024.13207
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