The Journal of Phytopharmacology, 2021;10(5):294-297 DOI:10.31254/phyto.2021.10504
Evaluation of concurrent exposure of lower concentrations of lead and endosulfan on apoptosis by scatter pattern of flow cytometry
V.Ranganathan1 , Jitendra Kumar. Malik2 , GS Rao3
1. Professor and Head, Department of Veterinary Pharmacology and Toxicology, Veterinary College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University, Orathanadu, Thanjavur-614 625, Tamil Nadu, India
2. Principal Scientist (Retired), Division of Veterinary Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, Bareilly -243122, Uttar Pradesh, India
3. Professor and University Head, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science, Tirupati- 517502, Andhra Pradesh, India
*Author to whom correspondence should be addressed.
Received: 9th July, 2021 / Accepted: 17th August, 2021
The effect of repeated exposure of lower doses of lead and endosulfan were evaluated on apoptosis in male wistar rats. Rats of group I served as untreated control. Group II received drinking water with lead as lead acetate @100 ppm (Pb100). Group III was given feed containing technical grade endosulfan @ 10 ppm (E10). Group IV was exposed to Pb (100) +E (10). Splenocytes were analysed for estimating apoptotic percentage in rats. The results suggest that apoptotic percentage was not changed in the lower doses of endosulfan and lead when administered alone and also in combination in the present study.
Lead, Endosulfan, Apoptosis.
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Ranganathan V, Malik JK, Rao GS. Evaluation of concurrent exposure of lower concentrations of lead and endosulfan on apoptosis by scatter pattern of flow cytometry. J Phytopharmacol 2021; 10(5):294-297. doi: 10.31254/phyto.2021.10504
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