The Journal of Phytopharmacology, 2018;7(1):10-12 ; DOI:10.31254/phyto.2018.7103
Effect of ethanolic extract of Reissantia indica on the human breast cancer cell line (MCF-7)
Gayathri P1 , Dhana Sekar V2 , Sudhakar K1 , Sangeetha M1 , Chamundeeswari D1
1. College of pharmacy, Sri Ramachandra University, Chennai, Tamil Nadu600116, India
2. Working as intern in Pfizer, Sriperumbudur, Chennai, Tamil Nadu602105, India
*Author to whom correspondence should be addressed.
Received: 23rd August, 2017 / Accepted: 10th December, 2017
Reissantia indica belongs to the family Celastraceae, is a native shrub to Maharashtra and Bengal, India. Its distinct plant parts are said to possess different activities, natives of Maharashtra and Bengal are using the plant parts for various purposes. In this experiment, the effect of ethanolic extract to destroy the cancer cells was studied. Study was carried on with human breast cancer cell line (MCF-7). Preparation of cell line was done using the reagents under standard protocol. Effect of plant extract on the cancer cells were recorded at two different timings (24 & 48 Hrs) respectively. Various doses of plant extract and standard were taken and introduced into cell line. Using 96 well plates the cells were seeded and studied for the viability. From the tabulated records, it clearly shows us the dose dependent response for the inhibition of cells. The maximum concentration of the plant extract 100µg/ml was found to be effective.
MCF-7, Cancer, Breast cancer, Cell line, Viability.
HOW TO CITE THIS ARTICLE
Gayathri P, Sekar VD, Sudhakar K, Sangeetha M, Chamundeeswari D. Effect of ethanolic extract of Reissantia indica on the human breast cancer cell line (MCF-7). J Phytopharmacol 2018; 7(1):10-12.
Creative Commons (CC) License-
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY 4.0) license. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (http://creativecommons.org/licenses/by/4.0/).
Copyright
Copyright © 2018 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0.