The Journal of Phytopharmacology, 2018;7(3):341-348 ; DOI:10.31254/phyto.2018.7318
Review on pharmacological activities and phytochemical constituents of Phyllanthus niruri (Amarus)
Danladi S1 , Idris MA2 , Umar II3
1. Department of Pharmaceutical & Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Bayero University, Kano, Nigeria
2. Department of Pharmacognosy & Herbal Medicine, Faculty of Pharmaceutical Sciences, Bayero University, Kano, Nigeria
3. Department of Clinical Pharmacy & Clinical Practice, Faculty of Pharmaceutical Sciences, Bayero University, Kano, Nigeria
*Author to whom correspondence should be addressed.
Received: 9th March, 2018 / Accepted: 26th April, 2018
Phyllanthus amarus Schum and Thonn (Euphobiaceae); is found in tropical and sub-tropical region of the world. It grows as a weed in moist abandoned land. It has various applications in tradition and folk medicine for treatment of various diseases such as hepatitis, cough, diuretic, menstruation problem and dysentery. It is commonly used by many countries across the world. Scientific investigation revealed that Phyllanthus amarus has potent activity against various diseases such as hepatitis B, HIV, microbial infections, plasmodiasis, nematode infestation, lithiasis, hyperlipidemia, diabetes, hyperuricemia, nephrotoxicity, platelet aggregation, radiation exposure, algesia, unwanted pregnancy, vasoconstriction, hepatotoxity and biological oxidation.
Phyllanthus amarus contains several phytochemical constituents such as alkaloid, flavonoid, terpenoids, cardiac glycoside, saponins, tannins, cyanogenic glycosides while proximate analysis showed that it contained high carbohydrate and fibre content.
Several important chemical compounds were isolated from Phyllanthus amarus such as phyllanthin, hypophyllanthin, Niranthin, Nirtetralin, phyltetralin phyllangin, nirphyllin, phyllnirurin and corilagin. Study showed that these compounds are responsible for several pharmacological activities.
Phyllanthus amarus, activity, disease, constituents.
HOW TO CITE THIS ARTICLE
Danladi S, Idris MA, Umar II. Review on pharmacological activities and phytochemical constituents of Phyllanthus niruri (Amarus) . J Phytopharmacol 2018; 7(3):341 -348 .
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