The Journal of Phytopharmacology, 2017;6(5):282-287 ;   DOI:10.31254/phyto.2017.6505

Research Article

Therapeutic activity of Thonningia sanguinea aqueous extract, Vahl on an experimental colibacillosis in chicken

Coulibaly Adama¹ , Kamagaté Tidiane² , Ouattara Abou^2,3 , Ouattara Karamoko² , Sanogo Moussa⁴ , Saraka N’Guessan Daniel⁵ , Ouattara Lacina⁶

Coulibaly Adama,Kamagaté Tidiane,Ouattara Abou,Ouattara Karamoko,Sanogo Moussa,Saraka N’Guessan Daniel,Ouattara Lacina

1. Biochemical Pharmacodynamy Laboratory, Biosciences Department, Felix Houphouët-Boigny University of Cocody, PO Box 582 Abidjan 22, Côte d’Ivoire
2. Biochemical Pharmacodynamy Laboratory, Biosciences Department, Felix Houphouët Boigny University of Cocody, PO Box 582 Abidjan 22, Côte d’Ivoire
3. Department of Biochemistry and Microbiology, Agroforestry Faculty, University Jean Lorougnon Guede of Daloa, PO Box 150 Daloa, Côte d’Ivoire
4. Central Veterinary Laboratory of Bingerville, PO Box 206, Bingerville, Côte d’Ivoire
5. Department of Environment and Health, Institut Pasteur of Côte d’Ivoire, PO Box 490 Abidjan 01
6. Biotechnology and Food microbiology Laboratory, University Nangui Abrogoua, Abidjan, PO Box 801 Abidjan 02, Côte d’Ivoire

*Author to whom correspondence should be addressed.

Received: 12th September, 2017 / Accepted: 24th October, 2017

Abstract

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Broiler breeding is faced with serious diseases, including colibacillosis, which is the leading cause of antibiotic therapy and the second leading cause of mortality in poultry after salmonellosis. It is caused by avian pathogens of E. coli. The objective of this study is to evaluate the effect of the aqueous extract of Thonningia sanguinea on certain therapeutic parameters in broiler chickens during experimental colibacillosis compared to a usual antimicrobial against colibacillary diarrhea (colistin). For each parameter, three lots of chicken meat were used: two treated batches, one with the plant extract and the other with colistin and one untreated contaminated batch (control). The study was spread over two weeks and for one week each chicken in the treated batch absorbed 500 mg of plant extract daily. The results show that the aqueous extract of this plant causes an improved clinical index, increased mean weight gain, reduced organ damage, elimination of germs in affected organs, and decreased mortality compared to the control group. On all the parameters, other than the moisture content, the plant extract had a more beneficial effect than colistin. Under these conditions, this plant could be used as a veterinary product to control avian colibacillosis.

Keywords

Thonningia sanguinea, E. coli, Colibacillosis, Broiler chickens.

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