The Journal of Phytopharmacology, 2015;4(3):147-151 ; DOI:10.31254/phyto.2015.4304
A comparative pharmacological study on the effect of Tagara (Valeriana wallichii) AND Jatamansi (Nardostachys jatamansi) in the management of anidra w.s.r to primary insomnia
Toolika E1 , Ravi M2 , Narayana Prakash B1 , Suhas Kumar Shetty1 , Ravishankar B2 , Savitha HP1
1. Department of Manasa Roga, SDM College of Ayurveda, Udupi574118, India
2. Department of Pharmacology & Toxicology, SDM Centre for Research in Ayurveda and Allied Sciences, Udupi-574118, India
*Author to whom correspondence should be addressed.
The present study was undertaken to evaluate Tagara and Jatamansi for certain CNS activities to ascertain the basis for their use as a sedative and hypnotics. The drugs were evaluated for hypnotic and sedative, anti anxiety, anti depressant and anti psychotic activities using standard experimental protocol. The data generated suggests that the test drugs Tagara and Jatamansi have complex CNS activity profile which is not easy to categorize under general CNS activity profile. Both possess significant anti-anxiety activity without significant sedative-hypnotic activity. This increases their utility for the patients suffering from anxiety due to sleep disturbances.
Tagara, Jatamansi, Hypnotic and sedative activity, Anti anxiety, Anti depressant.
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