The Journal of Phytopharmacology, 2021;10(6):496-499 DOI:10.31254/phyto.2021.10611

Research Article

Evaluation of acute oral toxicity of a herbal semen quality enhancer

Sunil Hajare¹ , Ranjit Suresh Ingole¹ , Mahesh Kumar Vitthal Ingawale¹ , Vivek Borekar¹ , David Kumar² , Ravikanth Kotagiri² , Bhaskar Ganguly²

Sunil Hajare,Ranjit Suresh Ingole,Mahesh Kumar Vitthal Ingawale,Vivek Borekar,David Kumar,Ravikanth Kotagiri,Bhaskar Ganguly

1. Post Graduate Institute of Veterinary and Animal Sciences (PGIVAS), Akola - 444104, India
2. Research and Development Unit, Ayurvet Limited, Baddi - 173205, India

*Author to whom correspondence should be addressed.

Received: 30th October, 2021 / Accepted: 16th December, 2021

Abstract

The objective of this study was to assess the acute oral toxicity of AV/SGB/27 (M/s Ayurvet Limited) in accordance with OECD-423 guideline. AV/SGB/27 is a herbal formulation for enhancing semen quality of livestock. Nine healthy and adult nulliparous nonpregnant Swiss albino female mice, weighing 24-28 g, were used in this study. After being given test material orally, the mice were examined for toxic effects and mortality. Changes in body weights, symptoms of toxicity, histological appearances of liver, kidney, and lungs, and biochemical parameters were used to assess the toxicity. No toxic effects or mortalities were noticed until the trial was completed, indicating that AV/SGB/27 is safe for oral consumption.