The Journal of Phytopharmacology, 2021;10(1):10-14 DOI:10.31254/phyto.2021.10103
In vitro antioxidant and anti-arthritic effect of the aqueous and ethanolic leaf and root bark extract of Alafia barteri
Ikeoluwapo Olanike Kolawole1 , Osareti Albert Taiwo Ebuehi2 , Esther Ayomide Awoyera2
1. Biochemistry Unit, Department of Biological Sciences, Mountain Top University, Ogun State, Nigeria
2. Biochemistry Department, College of Medicine, University of Lagos, Lagos State, Nigeria
*Author to whom correspondence should be addressed.
Received: 3rd December, 2020 / Accepted: 15th January, 2021
Alafia barteri (Apocynaceae) is a climbing shrub having white or pink flowers. Traditionally, it has been used to treat diseases like malaria, sickle cell anemia, and eye infections. This research is focused on investigating the antioxidant and anti-arthritic activities of the aqueous and ethanol leaf and root extract of Alafia barteri plant in vitro. In-vitro antioxidant methods used were 2, 2 -diphenyl-1-picrylhydrazyl assay, reducing power activity and hydrogen peroxide scavenging assay while the anti-arthritic activity was studied using the assay method of protein denaturation. Results revealed that aqueous and ethanol root extracts scavenge free radicals, thus inhibiting damage caused by oxidative stress in arthritis while the ethanol extracts of both the leaf and roots had good anti-arthritic activities as seen in its ability to decrease protein denaturation.
Alafia barteri, Anti-arthritic, Anti-oxidant, Denaturation.
HOW TO CITE THIS ARTICLE
Kolawole IO, Ebuehi OAT, Awoyera EA. In vitro antioxidant and antiarthritic effect of the aqueous and ethanolic leaf and root bark extract of Alafia barteri. J Phytopharmacol 2021; 10(1):10-14.