The Journal of Phytopharmacology, 2019;8(4):167-172 DOI:10.31254/phyto.2019.8404

Research Article

Pharmacognostical and analytical study of Kushmanda ghrita, a polyherbal formulation, for pharmaceutical standardization

Sabari Sengupta¹ , Anup Thakar² , C.R. Harisha³ , V.J. Shukla⁴

Sabari Sengupta,Anup Thakar,C.R. Harisha,V.J. Shukla

1. BAMS (C.U.), 3rd Year M.D. (Ayu) Scholar, Dept of Panchakarma, I.P.G.T.and R.A, GAU, Jamnagar, India
2. MD, PhD (Ayurveda). HOD, Panchakarma Department and Director, I.P.G.T.and R.A, GAU, Jamnagar, India
3. PhD Pharmacognosy, BMHS., Msc., PhD., HOD, Pharmacognosy Laboratory, I.P.G.T.and R.A, GAU, Jamnagar, India
4. PhD in Pharmaceutical, Msc. PhD, HOD, Pharmaceutical Chemistry Lab, I.P.G.T. and R.A, GAU Jamnagar, India

*Author to whom correspondence should be addressed.

Received: 1st July, 2019 / Accepted: 30th July, 2019

Abstract

Kushmanda Ghrita is a unique polyherbal Ayurvedic formulation recommended in the management of various psychological disorders mentioned in Astanga Hridaya and also in Bhaishajya Ratnavali and the formula given is the same, selected for present study. Aim of the study was to develop the pharmacognostical and physico-chemical profile of Kushmanda Ghrita. Kushmanda Ghrita was prepared as per classical methods in the Ayurvedic Pharmacy, I.P.G.T.andR.A., Gujarat Ayurved University, Jamnagar and analytical findings were systematically recorded. The samples were subjected to organoleptic, pharmacognostical analysis and physico-chemical analysis. Pharmacognostical study containing both macroscopic and powder microscopy of raw drugs of Kushmanda Ghrita and Physicochemical analysis of the finished product were carried out, to evaluate the quality of the formulation. Specific gravity of the formulation was 0.9205w/w, loss on drying at 1100 c temperature was 1.24%w/w, refractive index at 400 c was 1.473, HPTLC was carried out after organizing appropriate solvent system in which maximum 11 spots at 256 nm and 4 spots at 356 nm were distinguished. Results are further used for any other research works.