The Journal of Phytopharmacology, 2018;7(1):19-24 DOI:10.31254/phyto.2018.7105
Evaluation of anxiolytic activity of W. Chinensis Merrill Leaves
Kundan Singh Bora1 , Ankita Pant1
1. Department of Pharmacognosy, School of Pharmaceutical Sciences, Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences & Research, Balawala, Dehradun, Uttarakhand– 248001, India
*Author to whom correspondence should be addressed.
Received: 27th October, 2017 / Accepted: 11th December, 2017
Wedelia chinensis (family: Asteraceae), commonly known as Pilabhangra has been traditionally used for the treatment of various ailments like jaundice, diarrhoea, cephalahagia, respiratory disorders and to induce sleep, reduce the mental tension and in anxiety. Despite a long history of uses, no scientific pharmacological evaluation has ever been carried out on this plant. Thus, the present study was designed to evaluate anxiolytic activity of W. chinensis using different models of anxiety. Hydro-alcohol extract of W. chinensis leaves was prepared and subjected to bioactivity guided fractionation. Antioxidant activity was determined by spectrophotometric method. Total phenolic and flavonoid content were also estimated. Amongst the various fractions/extract of W. chinensis tested, only hydro-alcoholic extract, and its ethyl acetate fraction exhibited significant (P
Wedelia chinensis, anxiolytic activity, antioxidant activity, total flavonoid and phenolic content.
HOW TO CITE THIS ARTICLE
Bora KS, Pant A. Evaluation of anxiolytic activity of W. Chinensis Merrill leaves . J Phytopharmacol 201 8 ; 7 ( 1):19 -24 .
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