ISSN: 2320-480X
Manuscript Submission

The Journal of Phytopharmacology, 2014;3(4):254-258 DOI:10.31254/phyto.2014.3406

Research Article

Dose-dependent effect of Coriandrum sativum Linn. seeds on thermal pain stimulus

Sangeeta P Bhat1 , Waseem Rizvi1 , Anil Kumar1

1. Department of Pharmacology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh-202002, India

*Author to whom correspondence should be addressed.

Abstract


Aim- To evaluate the analgesic activity of the aqueous and ethanolic extracts Coriandrum sativum (C. sativum) seeds by thermal pain stimulus. Materials & methods- After an acute toxicity study performed as per OECD-425 Guidelines, doses of 100 mg/kg, 250 mg/kg and 500 mg/kg of each extract were selected. Wistar albino rats of either sex (100-200 g) were tested for the mean response time by Eddy’s hot plate method. Statistical significance (p

Keywords


Coriandrum sativum, Coriander seeds, Analgesic, Aqueous, Ethanolic.

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Copyright

Copyright © 2014 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0.

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