The Journal of Phytopharmacology, 2017;6(5):307-310 ; DOI:10.31254/phyto.2017.6510
Antimicrobial potential of fungal endophytes from selected high value medicinal plants of the Kashmir valley – India
Refaz Ahmad Dar1 , Iram Saba1 , Mohd Shahnawaz2 , Parvaiz Hassan Qazi1 , Inshad Ali Khan3
1. Division of Biotechnology, Indian Institute of Integrative Medicine (CSIR), Sanatnagar, Srinagar, Jammu & Kashmir-190005, India
2. Division of Plant Biotechnology, Indian Institute of Integrative Medicine (CSIR), Jammu - Tawi, Jammu & Kashmir180001, India
3. Division of Clinical Microbiology, Indian Institute of Integrative Medicine (CSIR), Jammu - Tawi, Jammu & Kashmir-180001, India
*Author to whom correspondence should be addressed.
Received: 7th October, 2017 / Accepted: 15th November, 2017
The purpose of this work was to evaluate the antimicrobial potential of endophytic fungi isolated from different high value medicinal plants of Kashmir valley. Evaluation of some endophytes has been carried for their possible antimicrobial activity from various parts of medicinal plants belonging to Kashmir valley (India). A total of twenty-eight fungal endophytes were isolated from the different parts of selected medicinal plants. Dichloromethane (DCM) extracts of all the morphologically different endophytes were prepared and subsequently checked for antimicrobial activities. Eight isolates showed good activity against gram positive bacteria with two isolates showing promising activity with MIC in the range of 0.5 – 1µg/ml. All the isolated endophytic extracts were completely devoid of antifungal activity. The seven-active endophytic fungal cultures were identified by ITS4 and ITS5 gene sequencing.
Endophyte, Antimicrobial, MIC.
HOW TO CITE THIS ARTICLE
Dar RA, Saba I, Shahnawaz M, Qazi PH, Khan IA. Antimicrobial potential of fungal endophytes from selected high value medicinal plants of the Kashmir valley – India. J Phytopharmacol 2017;6(5):307-310.
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